Executive Director, Global Market Planning and Operations

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Job Title: Executive Director, Global Market Planning and Operations

Department: Global Marketing

Location: Conshohocken, PA or Waltham, MA (hybrid)

About Madrigal Pharmaceuticals

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Job Description

The Executive Director, Global Market Planning & Operations is responsible for driving operational excellence/efficiency across the U.S. marketing team and guiding global strategic brand and asset planning. This role will oversee execution of key cross-marketing initiatives and will orchestrate global strategic planning for Rezdiffra and development assets. This global marketing leader will partner closely key stakeholders across the U.S. and global teams in commercial, medical and R&D to optimize planning and execution.

Key Responsibilities

1. Marketing Operations Leadership

• Identify, centralize and lead tactical execution of key U.S. marketing initiatives in close collaboration with HCP and DTC marketing functions, including both not limited to operations supporting HCP congresses, HCP speaker/patient programs, and sales force fulfillment.
• Serve as Promotional Review Committee (PRC) chair responsible for driving decision making at monthly and ad hoc PRC leadership committee; drive process improvements - inclusive of appropriate integration of AI - to drive consistency and efficiency of promotional reviews.

• Lead annual cross-functional Global brand planning process in collaboration with U.S., Global and International teams in Commercial, Medical, HEOR, Legal, Regulatory and Finance.
• Collaborate with HCP, DTC marketing and Strategy/Ops team to develop a holistic brand view on NPP (and in future omnichannel state) spend, ROI, and efficiency across channels.

2. Market Planning leadership

• Serve as the commercial representative at program teams for development assets, providing commercial input into established program teams including but not limited to guide target product profiles (TPPs) development, clinical development plans, and key asset go/no-go decisions.
• Partner closely with Commercial Strategy and Operations (CSO) team in aligning on customer insights and market research to drive assumptions on TPP development, commercial forecasting/valuations and scenario analyses to support R&D investment decisions.
• Own the early brand strategy and positioning for pipeline assets, including target patient segments, value propositions, and go-to-market strategies in close collaboration with CSO partners

3. Fostering Connectivity and Innovation

• Establish clear ways of working across Global and U.S. Marketing leadership with a focus on addressing operational inefficiencies, streamlining decision-making processes and propagating best practices.
• Help lead quarterly Global and U.S. Marketing touchpoints to share key initiatives, drive cross team
• Nurture innovative ideas and initiatives within teams to improve processes, strategies, and outcomes.

Required & Desired Qualifications

• Bachelor’s degree in Life Sciences, Business/Economics or a related field required; MBA or advanced degree preferred.
• Minimum of 20 years of experience with in-depth operating experience in Marketing, Strategic planning/New Product Planning, Marketing Operations with a significant experience in the U.S. market.
• Demonstrated track record of leading successful product launches, high-visibility, complex and impactful initiatives, and cross-functional teams in a complex, regulated environment.
• Strong analytical and strategic thinking skills with a results-driven, business-owner mindset.
• Exceptional leadership, written and verbal communication, and ability to influence without direct authority.
• Expertise in resource planning, performance management, and operational execution.

Key Competencies

• Strategic vision and ability to translate complex concepts into actionable plans.
• Exceptional organizational and problem-solving skills; ability to manage complexity and ambiguity.
• High emotional intelligence and aptitude for building strong relationships across diverse teams.
• Strong collaborative mindset with the ability to integrate and align multiple commercial functions.

Compensation

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands.  As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $276,000 - $337,000 per year.  We comply with all applicable minimum wage laws.

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.  

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. 

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com. 

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. 

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. 

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. 

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.  

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com.