Director, Patient Access Operations, Access & Reimbursement Case Managers
- Madrigal Pharmaceuticals
- Waltham, MA, USA
- Dec 09, 2025
Job Description
Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.
Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).
Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.
Director, Patient Access Operations, Access & Reimbursement Case Managers
Location : Waltham MA, Hybrid
Summary
This individual will report to the Head of Patient Access Operations and provide the operational leadership and oversight of the Access & Reimbursement Case Management (CM) team within Madrigal Patient Support (MPS). The Director will be responsible for executing a refined case management program, oversight of day-day activity of the case managers, and program performance.
Responsibilities
- Operate and oversee a Case Manager team that will conduct patient, HCP, payer, and SP outreach, and provide access, reimbursement, and affordability support to patients who have been prescribed a Madrigal drug and have enrolled in Madrigal Patient Support (MPS)
- Develop and implement KPIs and oversight mechanisms to ensure ongoing execution of program support and that operations meet Madrigal’s performance and quality expectations; Prepare and provide regular updates and business reviews for leadership and relevant cross-functional teams
- Partner with MPS vendors to create program materials, call guides, work instructions, and resources to direct operations of access, reimbursement, and affordability support for patients
- Develop and ensure alignment and compliance of Standard Operating Procedures across MPS offerings; Support preparation and execution of routine program audits
- Establish strong relationships and effective communication with key internal stakeholders and outside vendors to support development of program support offerings/materials and enable continuous improvement of patient access and experience
- Provide education/info to internal teams, HCPs, and patients, using materials and messaging approved for the audience, to create awareness of program offerings and support services
Qualifications
- Minimum of a bachelor's degree in related field or science, MBA or advanced degree preferred
- Five or more years of pharma/biotech experience in Market Access, Patient Support/Services, or Distribution, with hepatology/gastroenterology experience preferred
- Strong knowledge of health insurance; including managed care products, state and government provided benefits, and specialty medication distribution channels
- Prior supervisory or management experience required, preferably in the patient services space
- Experience with large specialty drug preferred, but not required
- Demonstrated experience adapting to change, navigating ambiguity, and executing with autonomy in these situations
- A self-starter, with a continuous improvement mindset, that drives progress, execution/delivery, and performance of initiatives/programs
- Passion for helping patients to navigate their medication and/or healthcare access journey
- Recognizes evolving shifts in market trends and respective effects on provider and patient
- Outstanding customer relationship, interpersonal, communication, and presentation skills with the ability to effectively work with diverse audiences and influence cross functionally
- Moderate level of travel required to vendor and home office sites
Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.
All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. The base salary range for this position is $210,000 - $257,000 per year.
All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.
Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws.
We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com.
Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.
Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.
Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.
Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.
Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com.
