Senior Director, Thought Leader Liaisons Northeast

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Senior Director, Thought Leader Liaisons (TLLs) – Northeast Region

Opportunity and Summary of Position:

Senior Director, Thought Leader Liaisons (TLLs) – Northeast Region The Senior Director of Thought Leader Liaisons (TLLs) at Madrigal Pharmaceuticals is a senior commercial leadership role, ideally suited for a highly experienced field leader with a strong track record of managing high-performing TLL teams and contributing to national strategy and execution. This position is focused on driving strategic direction, leading zone-level execution, and contributing key Thought Leader insights to support the launch of Resmetirom, a groundbreaking therapy for Metabolic Associated Steatohepatitis (MASH). The Northeast DTLL plays a critical role in transforming strategy into impactful action through exceptional team leadership, Thought Leader engagement, and cross-functional collaboration. Reporting to the VP of Thought Leader Liaisons, the Senior Director of TLLs will also serve as a key strategic voice within the broader commercial organization, helping to shape and implement national engagement strategy while ensuring operational excellence in the field. As with all employees, the Senior Director of TLLs is fully accountable for compliance with all laws, regulations, and policies that govern the conduct of Madrigal activities.

Position Responsibilities:

Main responsibilities include, but are not limited to:

Team Leadership and Coaching:

· Lead, coach, and develop a team of TLLs across the Northeast region, setting clear performance expectations and fostering continuous growth and excellence.

· Deliver regular field coaching, feedback, and support through one-on-ones, field rides, and development planning and implementation.

· Monitor and enhance team performance based on MBO metrics, and effectively translate activities into KPIs that demonstrate impact.

· Maintain a strong culture of accountability, compliance, and strategic alignment.

Launch Execution:

· Translate national brand strategy into tactical field execution plans at the zone level.

· Drive flawless launch performance through the TLL team’s engagement with key Thought Leaders, execution of regional initiatives, and collection of field insights.

· Identify local and regional opportunities, inform brand strategy adjustments, and ensure continuous optimization of field efforts.

· Ensure aligned pull-through of commercial strategy in coordination with Sales, Marketing, Market Access and other cross-functional zone leadership partners.

Resource Development and Deployment:

· Co-lead the development and field deployment of tools, training, and resources to elevate TLL effectiveness.

· Collaborate with national DTLLs and HQ stakeholders to ensure field resources are aligned and impactful.

· Act as a champion for innovation and feedback integration, continuously improving resources based on real-world Thought Leader input and regional needs.

National Strategy and Cross-Functional Leadership:

· Serve as a strategic thought partner to the VP of TLLs and peer DTLLs in shaping national TLL strategy, operations, and capability building.

· Represent regional perspectives in cross-functional forums and help drive consistent best practices across geographies.

· Collaborate closely with Marketing, Market Access, Sales Leadership, and Training to ensure integrated customer engagement and strategic alignment.

Qualifications and Skills:

· BA/BS Degree or higher in business, marketing, or life sciences.

· 15+ years of progressive commercial experience in the pharmaceutical, biotech, or healthcare industries.

· Minimum 5 years of experience leading field-based teams, preferably TLLs or Key Account Management.

· Demonstrated success launching specialty products and guiding teams through complex field execution.

· Deep understanding of the Thought Leader landscape in GI, Hepatology, and/or Metabolic Syndrome specialties.

· Proven ability to build, coach, and retain high-performing teams.

· Strategic, innovative thinker with strong business acumen and ability to drive zone-level execution

· Experience developing and deploying field tools, training content, and engagement resources.

· Knowledge of compliance and regulatory standards governing commercial engagement.

· Ability to travel extensively (60–75%) across the region and nationally as needed.

· A valid driver’s license is required based on role responsibilities

#LI-Remote

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. The base salary range for this position is $252,000 - $308,000 per year

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.  

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. 

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com. 

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. 

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. 

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. 

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.  

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com.