Executive Director, Health Technology

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Executive Director, Health Technology serves as the enterprise technical expert focused on accelerating the adoption and integration of Madrigal therapies within health system infrastructure, particularly Electronic Health Records (EHRs), clinical decision support tools, and digital workflows across Integrated Delivery Networks (IDNs).

This role will partner with Market Access, Medical, Marketing, Diagnostics, and Key Account Directors (KADs) to enable and operationalize pathway and protocol implementation through technology. The individual will work directly with health systems to ensure that approved protocols, diagnostics, and treatment pathways are effectively embedded into EHRs and care delivery workflows, reducing friction and accelerating time to therapy.

Key Responsibilities

1. Health Technology & EHR Strategy

• Serve as Madrigal’s subject matter expert on EHRs, clinical decision support, and health system technology infrastructure
• Develop strategies to integrate therapies, diagnostics, and care pathways into EHR systems (e.g., test order sets, alerts, documentation workflows)
• Identify opportunities to leverage technology to improve patient identification, prescribing efficiency, and time-to-therapy
• Define and advance Madrigal’s strategy for integrating AI/ML-driven capabilities within EHRs and digital health platforms to enable scalable patient identification, risk stratification, and clinical decision support
• Stay current on evolving health IT standards, interoperability, and digital health innovations impacting IDNs

2. IDN Technology Enablement

• Partner with KADs and account teams to support technology-driven pathway and protocol implementation within IDNs
• Engage directly with health system IT, informatics, and clinical operations leaders to facilitate adoption
• Translate clinical and access strategies into scalable, system-level technology solutions
• Support prioritization of accounts based on technical readiness and opportunity for impact

3. Cross-Functional Partnership

• Work closely with Marketing, Medical, Diagnostics, and Market Access to ensure alignment between strategy and technical execution in alignment with corporate and brand strategies
• Support field teams by providing technical expertise in account engagements and executive discussions
• Collaborate with Diagnostics to ensure testing workflows are integrated into EHR-driven patient identification processes

4. Workflow Optimization & Implementation

• Map and analyze end-to-end clinical and operational workflows within health systems to identify friction points
• Design and recommend technology-enabled solutions to streamline prescribing, approvals, and therapy initiation
• Champion the use of advanced analytics and AI/ML (including EHR-integrated algorithms, predictive modeling, and NLP) to drive scalable patient identification, stratification, and proactive care pathway optimization. Identify and address operational and technical barriers to adoption

5. Insights & Innovation

• Provide ongoing insights into health system technology trends, EHR capabilities, and digital adoption barriers
• Inform internal strategy by translating account-level learnings into scalable best practices
• Continuously assess emerging AI and digital health innovations (e.g., ambient AI, real-world data models, EHR-native algorithms) and translate them into actionable opportunities to accelerate diagnosis and treatment of MASH
• Partner with internal teams to evaluate and pilot innovative digital solutions that enhance access and adoption

6. Executive & Account Support

• Develop executive-ready materials to support IDN engagements involving technology and workflow integration
• Represent Madrigal as a technical expert in discussions with health system stakeholders
• Support strategic account planning by identifying technology-driven opportunities to differentiate and accelerate adoption

Qualifications

• Bachelor’s degree required; advanced degree (MBA, MPH, PharmD, MS in Health Informatics, or related field) preferred
• 15-18+ years of experience in health sciences industry (health systems, pharma/biotech or related work)
• 10+ years of experience in health IT, informatics, EHR/EMR integration, or digital health, within pharma/biotech, provider systems, or health technology companies
• Deep expertise in EMR systems (e.g., Epic, Cerner), clinical decision support, and health system workflows
• Experience with AI/ML applications in healthcare (e.g., EHR-based patient identification, real-world data analytics, or clinical decision support tools) strongly preferred
• Strong understanding of IDN structures and how technology supports clinical and operational decision-making
• Experience working cross-functionally and supporting complex account engagements
• Familiarity with diagnostics integration, data interoperability, and patient identification strategies

Core Competencies

• Technical & Informatics Expertise: Deep knowledge of EMRs, clinical workflows, and digital health solutions
• Health System Acumen: Understands how technology decisions are made and implemented within IDNs
• Strategic Enablement: Supports pathway adoption by translating strategy into technical execution
• Cross-Functional Collaboration: Effectively partners across internal teams and account stakeholders
• Problem Solving: Identifies and removes technical and operational barriers to adoption
• Executive Communication: Clearly articulates complex technical concepts to diverse audiences

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands.  As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $288,000 - $352,000 per year.  We comply with all applicable minimum wage laws.

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.  

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. 

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com. 

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. 

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. 

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. 

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.  

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com.